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Signal transduction pathways amplify the incoming signal by a signaling cascade using a network of enzymes that act on one another in specific ways to ultimately generate a precise and appropriate physiological response by the cell. A ligand-gated ion channel, upon binding with a ligand, changes conformation to open a channel in the cell membrane through which ions relaying signals can pass.

An example of this mechanism is found in the receiving cell of a neural synapse. The influx of ions that occurs in response to the opening of these channels induces action potentials, such as those that travel along nerves, by depolarizing the membrane of post-synaptic cells, resulting in the opening of voltage-gated ion channels.

Signal transduction

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Signal transduction - cell communication pathway

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